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Tolerability of high-dose topical tretinoin:. Participants were examined (by a study dermatologist) and interviewed every 6 months.Every month, the subjects in Prescrire’s Spotlight. 100 most recent:. For example, tretinoin is teratogenic while salicylic acid is fetotoxic.

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Topical tretinoin therapy was found to induce a significant decrease in the expression of p53 up to 6 months of therapy followed by a significant increase after 10.

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Results are permanent and may be seen in as little as 4-6 weeks with full results in 3-9 months. Retinoic Acid or Tretinoin is derived from Vitamin A. Retinol,.

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